Protein Synthesis
Proteins have broad applications ranging from antibodies and therapeutic proteins to enzymes and food alternative proteins. The extensive use of antibody drugs over the past two decades has made mammalian cells a popular host for production of high-value proteins. In recent years, the emergence of microbial alternative proteins has reignited research interest in microbial expression hosts.
We are committed to building the dvanced platform for protein production that integrates the cutting-edge synthetic biology technologies and artificial intelligence, aiming to achieve high-throughput and precision to design and manufacture functional proteins. By systematically integrating protein engineering, machine learning, and cell engineering, we have broken technical bottlenecks of traditional manufacturing methods, advancing customized protein production to an unprecedented level.
We vision a wide application of functional proteins in the fields of medicine, food, and medical aesthetics, endowing each product with exceptional precision and innovation. We believe that our technology innovation will accelerate transformation of protein industry, open a new chapter of a green, safe, and personalized functional protein, and underpin rapid growth of the protein sector.
Proteins are essential nutrients for the human body, and proper intake of protein helps achieve a healthy and balanced nutritional state. However, protein sources in human food are facing challenges such as limited resources, poor sustainability, and high prices. Among them, animal proteins consume substantial resources and exert a high environmental pressure, while plant proteins, plagued by limited essential nutrients and incomplete amino acid profile, struggle to meet the public demand.
Emerging protein sources, such as microbial and insect proteins, still face multiple challenges such as the low production scale, high cost, and low public acceptance.
To address these challenges, Biocreatech is committed to developing innovative synthesis methods for food alternative proteins. We combine protein design and synthetic biology to simultaneously achieve high performance and low cost for alternative proteins, leveraging cell engineering and precision fermentation platforms to realize high-efficiency and low-cost production.
Biocreatech is devoted to the development of functional protein-based cosmetic ingredients in the field of medical aesthetics, purportedly designed for precision skincare and sustainable beauty. With the increasing awareness of sensitive skin and the emerge of light medical aesthetics market, skin barrier repair has become a mainstream approach in skincare. As an important component of the skin extracellular matrix (ECM), glycoproteins possess crucial biological functions such as cell regeneration and repair.
Biocreatech has developed unique glycoprotein products through AI-aided precision design. This innovative protein integrates the structural characteristics of various functional molecules such as structural glycoproteins, soluble glycoproteins, and active glycans, facilitating exceptional repair efficacy. This innovative protein product comes naturally with strong intellectual property rights.
This innovative glycoprotein is based on synthetic biology and produced using yeasts that are generally regarded as safe (GRAS). Compared with glycoproteins derived from animal or plant extracts, it is intrinsically safer with distinctive green and sustainable characteristics.
In the field of therapeutic proteins, Biocreatech focuses on innovative treatment methods for metabolic rare diseases. Metabolic rare diseases are usually caused by genetic factors leading to defects or abnormalities in metabolic processes, such as abnormal metabolism of proteins, carbohydrates, and lipids. These conditions can result in severe health issues, including muscle atrophy, liver diseases, nervous system damage, and obesity.
In the field of metabolic rare diseases, Biocreatech focuses our R&D on innovative enzyme replacement therapy. A distinctive feature of our approach is that it achieves oral administration of enzymes, freeing patients from the pain of injections and facilitating their better adherence to long-term treatment. Compared with traditional approaches that rely on strict dietary interventions to reduce the frequency of disease episodes, the rare disease drug proteins developed by Biocreatech allow patients to maintain a normal diet, improve their quality of life, and bring joy to their lives.
Plant immune-stimulating proteins are a class of proteins that can activate the plant immune system and enhance disease resistance. They trigger defense signaling pathways in plants to strengthen disease-resistant responses, playing an important role in the "defense battle" between plants and pathogenic microorganisms.
Using advanced precise protein design technology, Biocreatech has developed plant immune-stimulating proteins that enable more efficient and environmentally friendly disease prevention and control. These proteins reduce the pressure of pesticide use, contributing to protecting the ecological environment and promoting the development of green agriculture.
